Category: Pharmacology

  • Atenção Farmacêutica: Contexto Atual, Exames Laboratoriais e by Paulo Caleb Junior de Lima Santos

    By Paulo Caleb Junior de Lima Santos

    Atenção Farmacêutica - Contexto Atual, Exames Laboratoriais e Acompanhmento Farmacoterapêutico insere-se na recomendação da Organização Mundial de Saúde - OMS como prática indispensável na relação paciente-medicamento. O livro tem como público-leitor Farmacêuticos e Graduados em Farmácia orientando-os com muita segurança para o exercício da atenção farmacêutica.
    Show description

  • Methylxanthines: 200 (Handbook of Experimental Pharmacology) by Bertil B. Fredholm

    By Bertil B. Fredholm

    within the current quantity of the instruction manual of Experimental Pharmacology renowned specialists describe the activities of other xanthines with a spotlight on caffeine and theophylline. a different bankruptcy is dedicated to theobromine, an lively part of chocolate, the activities of that are much less good characterised. This ebook additionally provides the pharmacology of 1 xanthine spinoff, propentofylline, for example of a xanthine that has passed through large improvement for a unique healing area.
    Show description

  • Perry's The Chemotherapy Source Book by Michael C. Perry,Donald C. Doll,Carl E. Freter,Michael C

    By Michael C. Perry,Donald C. Doll,Carl E. Freter,Michael C Perry

    Perry’s The Chemotherapy resource booklet, now in its 5th variation, presents details at the number of chemotherapeutic brokers, using mix chemotherapy, and the toxicity of person medications. geared up via website, this can be the single booklet of its type to concentration strictly at the medical perform of chemotherapy, and is intended to function a “one-stop store” for info on selection of chemotherapeutic brokers, therapy outlines, grading of unintended effects, and dose modification.
    Show description

  • NAPLEX Nuggets: Your Essential Review of the Most Highly by Eric Christianson,Melissa Christianson

    By Eric Christianson,Melissa Christianson

    I bear in mind what it was once wish to learn for the NAPLEX. Overwhelming doesn’t start to describe the sensation. the place do you begin? How do you prioritize and assessment for this significant examination? whilst i'm getting ready to take pharmacy tests, i've got a truly tricky time studying and holding info from significant assessment books. i locate myself studying for 5-10 mins and my brain starts off to wander, keeping not anything of what I simply learn. After years of perform and attempt taking (NAPLEX, BCPS, CGP etc.), i've got stumbled on that I research such a lot successfully by way of memorizing details in brief vital bullet issues. during this research consultant, i've got chosen the main familiar drugs sessions and feature supplied you with my such a lot hugely testable pearls on each one category. during this booklet, I conceal over one hundred fifty drugs sessions which include approximately four hundred drugs! i've got created bullet issues in order to assist you evaluation extra successfully and never waste your constrained research time. This source isn't really meant to be a package deal insert for each medicine, yet relatively the way to attempt to prioritize your research approach and comprehend the most important “nuggets” of knowledge you should understand that can assist you move the NAPLEX. The rationale is to offer you a short, particularly useful assessment of an important drugs you'll likely be established at the NAPLEX examination. i actually desire this booklet is helping you cross the NAPLEX the 1st time! NAPLEX is a registered trademark of NABP. Meded101 and this research consultant aren't affiliated or counseled by means of NABP or the NAPLEX Exam.
    Show description

  • Evolution-adjusted Tumor Pathophysiology:: The Novel by Albrecht Reichle

    By Albrecht Reichle

    mixed modularized remedies for metastatic melanoma are pointing to principal difficulties of verbal exchange between ‘systems participators’. A conversation thought explains 'social engineering', endogenously caused or by way of imposing non-normative boundary stipulations. Evolution-adjusted tumor pathophysiology is borne via an evolution thought, which contrasts narrative evolution histories. The software of rationalizations constituting the tumor's normativity (inflammation, immune reaction etc.) represents the non-genomic counterpart of the tumor genome and will be also assessed in the course of tumor staging. Evolution-adjusted tumor pathophysiology permits enforcing utilized structures biology, a singular scientific and pharmaceutical expertise for bioengineering tumor reaction and personalizing tumor remedy. mixed modularized treatment, evolution-adjusted tumor pathophysiology, and ‘universal’ biomarkers concertedly deal with genetically established tumor heterogeneity.
    Show description

  • Recent Advances in Neuropsycho-Pharmacology: Selected Papers by B. Angrist,G. D. Burrows,M. Lader

    By B. Angrist,G. D. Burrows,M. Lader

    fresh Advances In Neuropsychopharmacology comprises chosen papers from the twelfth Congress of the Collegium Internationale Neuro-Psychopharmacologicum held in Gõteborg, Sweden, 22-26 June 1980. The forty seven papers within the quantity are geared up into six components. The papers partially I take care of the topic of psychostimulants in psychiatric study. themes lined contain the impact of persistent d-amphetamine and protracted apomorphine therapy on non-human primate social and solitary habit; and the behavioral results of dopamine agonists. half II assesses the prescription of psychotropic medicines through common practitioners. half III examines blood platelets as a version procedure for important monoaminergic neurons. half IV specializes in anxiousness pathways within the mind. half V considers customers for a biochemical category process in psychiatry. half VI offers pharmacokinetic reviews of psychotropic medicines. half VI comprises papers at the renal functionality and renal histology of lithium sufferers on upkeep lithium remedy and pre-lithium sufferers; and the remedy of refractory schizophrenia.
    Show description

  • Preformulation in Solid Dosage Form Development (Drugs and by Moji Christianah Adeyeye,Harry G. Brittain

    By Moji Christianah Adeyeye,Harry G. Brittain

    During the onset of any scientific trial there are various components and variables to contemplate. investment, time restraints, and regulatory corporation guidance are elements that regularly impact which variables might be studied, leaving different very important details out of the examine. Preformulation in good Dosage shape Development covers each subject of serious significance to the preformulation phases of drug improvement. Serving as a instruction manual or stand-alone reference, this article equips these in academia and the pharmaceutical with either simple and utilized rules for the characterization of gear, excipients, and items, and bargains with the problems with regards to predictability, id, and product improvement in the course of preformulation phases via part I of medical trials.


    With contributions from a world panel of specialists within the box, this guide:




    • outlines an up to date preformulation software for contemporary drug improvement matters that comes with particle morphology, characterization, thermal research, and solubility methods

    • contains rational designs for the constitution of formula studies

    • covers the significance of preformulation layout utilizing synthetic neural networks and computational prediction suggestions, and examines the techniques of preliminary-preformulation

    • discusses the common drug-excipient interactions which may take place in the course of the process improvement and techniques of characterization

    • includes novel ways to make sure the actual and chemical balance of recent formulations

    • reviews the constitution, content material, and structure of the preformulation report

    • examines the importance of drug substance physiochemical houses, in regulatory caliber through design
    Show description

  • Back and Neck Pain (Oxford American Pain Library) by Bill McCarberg,Steven Stanos,Yvonne D'Arcy

    By Bill McCarberg,Steven Stanos,Yvonne D'Arcy

    An anticipated 60 million americans be afflicted by ache. there was an explosion in ache study, new prescribed drugs, the popularity of complementary and substitute remedies, interventional innovations and surgical procedure, expert soreness societies and companies with services in soreness administration. nonetheless, the commonest visible in fundamental care settings and in soreness clinics is returned soreness. regardless of the excessive incidence of again and neck discomfort within the inhabitants, remedy and ongoing administration of those stipulations maintains to pose demanding situations in a number of medical settings. academic assets for either basic and professional clinicians alike are had to handle those challenges.

    As a part of the Oxford American discomfort Library, this sensible instruction manual is designed to function a concise but authoritative source on diagnosing and treating again and neck soreness. Co-authored by means of fundamental care physicians and a nurse practitioner with vast services in ache drugs and administration, the booklet is adapted to the desires of busy future health care pros treating sufferers within the basic care atmosphere, and makes a speciality of crucial scientific details for physicians and different healthcare execs who see sufferers with those frequent and sometimes debilitating stipulations. as well as masking all points of prognosis, treatmentboth pharmacological and non-pharmacological, and ongoing administration of again and neck soreness, the guide additionally positive factors chapters devoted to related stipulations of myofascial soreness, whiplash and fibromyalgia.
    Show description

  • Thermodynamics and Kinetics of Drug Binding, Volume 65 by György Keserü,David C. Swinney

    By György Keserü,David C. Swinney

    This sensible reference for medicinal and pharmaceutical chemists combines the theoretical history with glossy tools in addition to purposes from fresh lead discovering and optimization initiatives.
    Divided into elements at the thermodynamics and kinetics of drug-receptor interplay, the textual content offers the conceptual and methodological foundation for characterizing binding mechanisms for medicinal drugs and different bioactive molecules. It covers all presently used tools, from experimental methods, corresponding to ITC or SPR, correct as much as the newest computational tools. Case reviews of real-life lead or drug improvement tasks also are integrated so readers can observe the equipment discovered to their very own initiatives. eventually, some great benefits of a radical binding mode research for any drug improvement venture are summarized in an outlook bankruptcy written through the editors.
    Show description

  • EGF Receptor in Tumor Growth and Progression (Ernst Schering by R.B. Lichtner,R.N. Harkins

    By R.B. Lichtner,R.N. Harkins

    The final 15 years have introduced an figuring out of development and differentiation on the molecular point, increasing our wisdom of the beginning and development of melanoma. Early breakthroughs defining development regulate pathways got here through reports of oncogenes, mutated signaling molecules that experience misplaced the potential to tum off their proliferative sign. Oncogenes with varied growth-promoting actions were chanced on, overlaying the gamut from mobile floor to nuclear signaling. Sequencing of those oncogenes printed that they have been mutated sorts of captured mobile genes and displayed tyrosine kinase job. The epidermal development issue (EGF) receptor used to be the 1st of 40-50 transmembrane tyrosine kinase receptors to be cloned and sequenced. past telephone proliferation, activation of EGF receptor by way of its particular ligands controls vital physiological techniques, akin to phone differentiation, apoptosis, mobile migration, and phone form. Activation of autocrine development loops, consisting in stable human tumors of upregulated expression of EGFR including elevated creation of ligands urged its an important position in self sufficient tumor growth.
    Show description