Thermodynamics and Kinetics of Drug Binding, Volume 65 by György Keserü,David C. Swinney

By György Keserü,David C. Swinney

This sensible reference for medicinal and pharmaceutical chemists combines the theoretical history with glossy tools in addition to purposes from fresh lead discovering and optimization initiatives.
Divided into elements at the thermodynamics and kinetics of drug-receptor interplay, the textual content offers the conceptual and methodological foundation for characterizing binding mechanisms for medicinal drugs and different bioactive molecules. It covers all presently used tools, from experimental methods, corresponding to ITC or SPR, correct as much as the newest computational tools. Case reviews of real-life lead or drug improvement tasks also are integrated so readers can observe the equipment discovered to their very own initiatives. eventually, some great benefits of a radical binding mode research for any drug improvement venture are summarized in an outlook bankruptcy written through the editors.

Show description

Read or Download Thermodynamics and Kinetics of Drug Binding, Volume 65 (Methods and Principles in Medicinal Chemistry) PDF

Best pharmacology books

Modern Strategy for Preclinical Pharmaceutical R&D: Towards the Virtual Research Company

The 20th century has been a good luck for contemporary drugs, and has led to the iteration of a plethora of gear to regard commonest health problems. even though, within the mild of accelerating regulatory calls for, spiralling expenditures and diminishing advertisement returns, the query of the way, whilst, the place and no matter if to behavior pharmaceutical R&D has profound implications, and never only for these in the pharmaceutical undefined.

The SAGE Handbook of Healthcare (Sage Handbooks)

With escalating healthcare charges, alterations to the regulatory keep watch over on pharmaceutical industries and the inevitable alterations made in rules and funding in healthcare there's huge, immense curiosity within the advertisement in addition to the clinical elements of cutting-edge healthcare undefined. The SAGE instruction manual of Healthcare presents an authoritative research of the present (and expected) advancements within the worldwide healthcare industries.

Carbon Monoxide Poisoning

Whereas an ever-present and commonly used toxin, carbon monoxide (CO) is still the number 1 poison in our environment.  This silent killer is chargeable for over 2,000 deaths a yr within the usa on my own. the general public and healthcare groups desire caliber information regarding the various hazards offered via carbon monoxide publicity.

Self-Medication and Society: Mirages of Autonomy (Routledge Studies in the Sociology of Health and Illness)

The query of recourse to self-medication arises on the intersection of 2 in part opposed discourses: that of the general public gurus, who suggest the perform essentially for financial purposes, and that of overall healthiness execs, who condemn it for worry that it could pose a possibility to well-being and dispossess the career of craftsmanship.

Additional resources for Thermodynamics and Kinetics of Drug Binding, Volume 65 (Methods and Principles in Medicinal Chemistry)

Example text

Download PDF sample

Rated 4.42 of 5 – based on 36 votes