By György Keserü,David C. Swinney
Divided into elements at the thermodynamics and kinetics of drug-receptor interplay, the textual content offers the conceptual and methodological foundation for characterizing binding mechanisms for medicinal drugs and different bioactive molecules. It covers all presently used tools, from experimental methods, corresponding to ITC or SPR, correct as much as the newest computational tools. Case reviews of real-life lead or drug improvement tasks also are integrated so readers can observe the equipment discovered to their very own initiatives. eventually, some great benefits of a radical binding mode research for any drug improvement venture are summarized in an outlook bankruptcy written through the editors.
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